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Young Chul Chung Selected Research

Changkil

2/2015Saponins, especially platyconic acid A, from Platycodon grandiflorum reduce airway inflammation in ovalbumin-induced mice and PMA-exposed A549 cells.
6/2013Platycodi Radix attenuates dimethylnitrosamine-induced liver fibrosis in rats by inducing Nrf2-mediated antioxidant enzymes.
5/2012Platycodi Radix suppresses development of atopic dermatitis-like skin lesions.
11/2006Inhibition of tumor invasion and metastasis by aqueous extract of the radix of Platycodon grandiflorum.
8/2006Chemopreventive effect of saponins derived from roots of Platycodon grandiflorum on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice.
1/2006Inhibition of tumor necrosis factor-alpha-induced expression of adhesion molecules in human endothelial cells by the saponins derived from roots of Platycodon grandiflorum.

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Young Chul Chung Research Topics

Disease

11Neoplasms (Cancer)
03/2019 - 10/2009
8Inflammation (Inflammations)
11/2019 - 12/2004
6Atopic Dermatitis (Atopic Eczema)
07/2014 - 09/2011
5Fibrosis (Cirrhosis)
01/2017 - 12/2004
4Neoplasm Metastasis (Metastasis)
03/2019 - 11/2006
4Breast Neoplasms (Breast Cancer)
11/2018 - 05/2014
4Necrosis
03/2009 - 12/2004
3Atherosclerosis
11/2019 - 01/2006
3Fibrosarcoma
03/2019 - 10/2010
3Alcoholic Fatty Liver
08/2018 - 02/2017
3Liver Cirrhosis (Hepatic Cirrhosis)
01/2017 - 11/2010
3Dermatitis
07/2014 - 03/2013
3Obesity
12/2011 - 10/2009
2Psychotic Disorders (Schizoaffective Disorder)
01/2022 - 02/2021
2Osteoporosis
01/2019 - 01/2017
2Carcinogenesis
10/2014 - 08/2006
2Skin Diseases (Skin Disease)
08/2012 - 09/2011
2Constipation
02/2010 - 10/2009
2Melanoma (Melanoma, Malignant)
02/2010 - 11/2006
1Liver Diseases (Liver Disease)
11/2019
1Asthma (Bronchial Asthma)
01/2017
1Vascular Diseases (Vascular Disease)
02/2016
1Colonic Neoplasms (Colon Cancer)
09/2014
1Carcinoma (Carcinomatosis)
01/2014
1Metabolic Diseases (Metabolic Disease)
03/2013
1Body Weight (Weight, Body)
12/2011
1Weight Gain
12/2011

Drug/Important Bio-Agent (IBA)

13SaponinsIBA
11/2019 - 01/2006
6ChangkilIBA
02/2015 - 01/2006
6AntioxidantsIBA
06/2013 - 01/2011
5Immunoglobulin E (IgE)IBA
07/2014 - 06/2009
4Messenger RNA (mRNA)IBA
08/2017 - 03/2013
4Dimethylnitrosamine (Nitrosodimethylamine)IBA
01/2017 - 11/2010
4Dinitrochlorobenzene (DNCB)IBA
07/2014 - 05/2012
4CytokinesIBA
01/2014 - 01/2006
4Anthocyanins (Anthocyanin)IBA
12/2011 - 11/2010
3Pharmaceutical PreparationsIBA
10/2014 - 05/2011
3Interleukin-4 (Interleukin 4)IBA
07/2014 - 03/2013
3Interleukin-5 (Interleukin 5)IBA
07/2014 - 03/2013
3Interleukin-13IBA
07/2014 - 03/2013
3Biological ProductsIBA
07/2014 - 05/2011
3Aspartate Aminotransferases (Aspartate Transaminase)IBA
06/2013 - 12/2004
3Matrix Metalloproteinase 9 (Gelatinase B)IBA
05/2011 - 02/2010
2Polytetrafluoroethylene (Teflon)FDA Link
01/2022 - 02/2021
2Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
11/2019 - 02/2016
2p38 Mitogen-Activated Protein KinasesIBA
03/2019 - 09/2014
2kahweolIBA
03/2019 - 11/2018
2platycodin DIBA
01/2019 - 01/2017
2LeptinIBA
08/2017 - 05/2014
2Proteins (Proteins, Gene)FDA Link
08/2017 - 10/2014
2OvalbuminIBA
01/2017 - 02/2015
2LigandsIBA
10/2014 - 05/2014
2CollagenIBA
06/2013 - 11/2010
2Alanine Transaminase (SGPT)IBA
06/2013 - 11/2010
2Triglycerides (Triacylglycerol)IBA
12/2011 - 11/2009
2Ethanol (Ethyl Alcohol)IBA
11/2009 - 03/2009
2DNA (Deoxyribonucleic Acid)IBA
06/2008 - 05/2008
1Nitric Oxide (Nitrogen Monoxide)FDA Link
11/2019
1phorbolIBA
03/2019
1Fatty Acid Synthases (Fatty Acid Synthase)IBA
11/2018
1Epidermal Growth Factor (EGF)IBA
11/2018
1CaspasesIBA
11/2018
1Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA
08/2018
1Oxidoreductases (Dehydrogenase)IBA
08/2018
1Aromatase InhibitorsIBA
08/2017
1Aromatase (CYP19)IBA
08/2017
1Estrogens (Estrogen)FDA Link
08/2017
1Estradiol (Delestrogen)FDA LinkGeneric
08/2017
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
08/2017
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
08/2017
1Capsaicin (Zostrix)FDA Link
01/2017
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
01/2017
1PPAR gammaIBA
01/2017
1theanineIBA
01/2017
1Betulinic AcidIBA
02/2016
1TriterpenesIBA
02/2016
1platyconic acidIBA
02/2015
1AllergensIBA
02/2015
1Cytochrome P-450 CYP1A1 (CYP1A1)IBA
10/2014
1Polychlorinated Dibenzodioxins (TCDD)IBA
10/2014
1Metformin (Glucophage)FDA LinkGeneric
10/2014
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
10/2014
1XenobioticsIBA
10/2014
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
10/2014
1ilimaquinoneIBA
09/2014
1Death Domain ReceptorsIBA
09/2014
1Caspase 8 (Caspase-8)IBA
09/2014
1Heme Oxygenase-1IBA
07/2014
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2014
1Malondialdehyde (Propanedial)IBA
06/2013
1GinsenosidesIBA
06/2013
1EnzymesIBA
06/2013
1Anti-Allergic Agents (Antiallergic Agents)IBA
06/2013
1AMP-Activated Protein KinasesIBA
03/2013
1Chemokine CCL17IBA
03/2013
1PolyphenolsIBA
03/2013
1LipidsIBA
12/2011
1ethyl acetateIBA
09/2011

Therapy/Procedure

3Traditional Medicine (Folk Remedies)
02/2010 - 01/2009
1Therapeutics
11/2019